Sports News
Latest sports headlines and breaking news from Canada and around the world
Latest Sports News
Latest News
View All
Jones out for Olympics, replaced by LaCombe on Team USA
Ducks defenseman added to roster for Milano Cortina Games

Prince of Persia Remake Game Canceled Amid Ubisoft Reorg, Layoffs
After weeks of speculation following reported studio closures and rounds of layoffs, French video game publisher Ubisoft announced Wednesday it is launching a reorganization of the company

Scientists uncover hidden cells fuelling brain cancer - and a drug that could stop them
A Canadian team led by scientists from McMaster and the Hospital for Sick Children has uncovered a new way to slow the growth of glioblastoma, the most aggressive and currently incurable form of brain cancer – and identified an existing medication that could treat it. Certain brain cells — once thought to simply support healthy [...]Read More...

Bills owner Terry Pegula pins Keon Coleman pick on coaching staff
Team owner Terry Pegula, at a press conference with general manager Brandon Beane on Wednesday, told reporters that the decision to draft Cole shouldn't fall on the front office's shoulders, and that the former coaching staff under Sean McDermott should be at fault.
20-Year-Old Man Dies of Flesh-Eating Disease After Doctors Dismissed 'Red Flag' Symptoms as Tonsillitis
Luke Abrahams died on Jan. 23, 2023, just days after medics said he didn't need to be taken to the hospital

Canadian wins life-changing $15-million Lotto Max jackpot
A lucky Lotto Max player in Canada just woke up to a life-changing surprise after scoring the latest jackpot.

NHL On Tap: Kane 3 points from U.S. record with Red Wings visiting Maple Leafs
MacKinnon chasing Richard, Ross trophies; Penguins try to keep climbing Metropolitan Division

Lithium study yields insights in the fight against HIV
Study in human cells finds low-cost drug keeps virus dormant through an unexpected pathway, pointing the way to new treatments Lithium, a widely used treatment for bipolar disorder and other mood disorders, has shown early promise in suppressing HIV, McGill University researchers report. A new study published in iScience found lithium can prevent infected cells from reactivating, and that it does so through an unexpected biological mechanism. The findings point toward future treatments designed to mimic lithium’s beneficial effects while avoiding its broader impacts on the body. “One major thrust in HIV cure research is asking whether existing drugs can be repurposed. Because lithium is inexpensive and already approved for other uses, it offers a faster starting point than developing a new drug from scratch,” said senior author Andrew Mouland, Professor in McGill’s Department of Medicine and Head of the HIV-1 RNA Trafficking Laboratory at the Lady Davis Institute for Medical Research. The results do not mean people with HIV should take lithium, he said. The psychoactive drug can cause significant side effects and has not yet been tested in humans as an HIV treatment. A step toward a ‘functional cure’ An estimated 40.8 million people around the world were living with HIV in 2024. Even with effective antiretroviral therapy, the virus can remain hidden in immune cells and rebound if daily treatment stops. A “functional cure” aims to overcome this challenge. Rather than eliminating the virus entirely, the goal is to keep HIV dormant, so it cannot restart infection, potentially reducing the need for continuous daily medication. “In our experiments, lithium directly suppressed HIV reactivation in lab-grown human cells, something that had not been clearly demonstrated before,” said first author Ana-Luiza Abdalla, who conducted the work as a PhD student at McGill and is now a postdoctoral fellow at the Montreal Neurological Institute. As well, the team gained new insights into the mechanism involved. Earlier research suggested lithium might work by activating autophagy, the cell’s recycling system. Because many drugs studied in HIV cure research affect this pathway, scientists assumed autophagy was responsible for keeping the virus dormant. This study challenges that assumption, made possible by a fluorescence-based test developed by University of Manitoba researcher Thomas Murooka that allows scientists to distinguish between dormant and active virus in cells. “What surprised us was that the effect persisted even when we disrupted autophagy,” Abdalla said. “That suggests other pathways are involved, possibly ones HIV relies on to restart.” About the study “Lithium attenuates HIV-1 latency reversal in an autophagy-independent way” by Ana-Luiza Abdalla, Gabriel Guajardo-Contreras, Meijuan Niu, Thomas Murooka and Andrew J. Mouland was published in iScience. Funding was provided by the Canadian Institutes of Health Research.
Toronto Weather
TSX Index
CAD Exchange
More Sports Coverage
Local News

Xbox 'Developer Direct Sale' Now Live With Big Discounts On Xbox Game Studios Titles
Microsoft debuts a new Dev Direct sale - Ahead of Xbox Developer Direct airing tomorrow, January 22nd, the Microsoft Store is hosting a new Dev Direct sale -...

Manchester City: Squad to refund ticket costs for fans after Champions League loss
The Manchester City squad will refund the ticket costs for 374 supporters who travelled to Norway to witness their side's shock 3-1 Champions League defeat at Bodo/Glimt on Tuesday.

Donkey Kong Country Returns HD Gets Free Switch Update and Switch 2 Upgrade
Donkey Kong Country Returns HD gets a massive Switch 2 boost with Local GameShare and the addition of Dixie Kong.
Amazon shoppers call this bestselling massage gun a 'game-changer' - it has 1,000s of 5-star reviews, and it's 50% off right now
"Pain and stress are gone."
Stay Updated
Get the latest news delivered directly to your inbox

